Activation of DNA Damage Tolerance Pathways May Improve Immunotherapy of Mesothelioma

SIMPLE SUMMARY: A critical step in the success of immunotherapy is the presentation of tumor-derived peptides by the major histocompatibility complex I (MHC-I) of tumor cells. These neoantigens are potentially immunogenic and trigger immune responses orchestrated by cytotoxic cells. In malignant mes...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Brossel, Hélène, Fontaine, Alexis, Hoyos, Clotilde, Jamakhani, Majeed, Willems, Mégane, Hamaidia, Malik, Willems, Luc
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Opinion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269013/
https://ncbi.nlm.nih.gov/pubmed/34199066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133211
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