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LncRNA SOX2OT alleviates mesangial cell proliferation and fibrosis in diabetic nephropathy via Akt/mTOR-mediated autophagy

BACKGROUND: Accumulating evidences have demonstrated that long non-coding RNAs (lncRNAs) are involved in the pathophysiology of diabetic nephropathy (DN). lncRNA SOX2OT plays an essential role in many diseases, including diabetes. Herein, we aim to investigate the underlying mechanism of lncRNA SOX2...

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Publicado en:Mol Med
Main Authors: Chen, Ke, Yu, Bo, Liao, Jie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268185/
https://ncbi.nlm.nih.gov/pubmed/34238205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-021-00310-6
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