The Involvement of Insulin-Like Growth Factor 1 and Nerve Growth Factor in Alzheimer’s Disease-Like Pathology and Survival Role of the Mix of Embryonic Proteoglycans: Electrophysiological Fingerprint, Structural Changes and Regulatory Effects on Neurotrophins

Alzheimer’s disease (AD)-associated neurodegeneration is triggered by different fragments of amyloid beta (Aβ). Among them, Aβ (25–35) fragment plays a critical role in the development of neurodegeneration—it reduces synaptic integrity by disruption of excitatory/inhibitory ratio across networks and...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Aghajanov, Michail, Matinyan, Senik, Chavushyan, Vergine, Danielyan, Margarita, Karapetyan, Gohar, Mirumyan, Margarita, Fereshetyan, Katarine, Harutyunyan, Hayk, Yenkoyan, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267974/
https://ncbi.nlm.nih.gov/pubmed/34209299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22137084
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