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Disruption of Cholinergic Circuits as an Area for Targeted Drug Treatment of Alzheimer’s Disease: In Vivo Assessment of Short-Term Plasticity in Rat Brain

The search for new therapeutics for the treatment of Alzheimer’s disease (AD) is still in progress. Aberrant pathways of synaptic transmission in basal forebrain cholinergic neural circuits are thought to be associated with the progression of AD. However, the effect of amyloid-beta (Aβ) on short-ter...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Chavushyan, Vergine, Soghomonyan, Ani, Karapetyan, Gohar, Simonyan, Karen, Yenkoyan, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600922/
https://ncbi.nlm.nih.gov/pubmed/33050228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13100297
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