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Current Understanding of IL-37 in Human Health and Disease
IL-37 is a recently discovered cytokine in the IL-1 family exerting broad protective effects on inflammatory diseases, autoimmune diseases, and cancer. Immune and non-immune cells produce the IL-37 precursor upon pro-inflammatory stimuli. Intracellularly, caspase-1 cleaves and activates IL-37, and i...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8267878/ https://ncbi.nlm.nih.gov/pubmed/34248996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.696605 |
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