Clinical and Molecular Heterogeneity in Patients with Innate Resistance to Anti-PD-1 +/− Anti-CTLA-4 Immunotherapy in Metastatic Melanoma Reveals Distinct Therapeutic Targets

SIMPLE SUMMARY: Immune checkpoint therapies have significantly improved the survival of patients with metastatic melanoma, however approximately 50% of patients exhibit no response. Understanding the underlying clinical, pathologic and genetic factors associated with failed response to immunotherapi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cancers (Basel)
Κύριοι συγγραφείς: Gide, Tuba N., Pires da Silva, Inês, Quek, Camelia, Ferguson, Peter M., Batten, Marcel, Shang, Ping, Ahmed, Tasnia, Menzies, Alexander M., Carlino, Matteo S., Saw, Robyn P. M., Thompson, John F., Scolyer, Richard A., Long, Georgina V., Wilmott, James S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2021
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267740/
https://ncbi.nlm.nih.gov/pubmed/34202352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133186
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