Integrated molecular and immunophenotypic analysis of NK cells in anti-PD-1 treated metastatic melanoma patients

Purpose: Anti-PD-1 therapy has revolutionized the treatment and improved the survival of stage IV melanoma patients. However, almost half of the patients fail to respond due to immune evasive mechanism. A known mechanism is the downregulation of major histocompatibility complex (MHC) class I express...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Lee, Hansol, Quek, Camelia, Silva, Ines, Tasker, Annie, Batten, Marcel, Rizos, Helen, Lim, Su Yin, Nur Gide, Tuba, Shang, Ping, Attrill, Grace H., Madore, Jason, Edwards, Jarem, Carlino, Matteo S., Guminski, Alexander, Saw, Robyn P.M., Thompson, John F., Ferguson, Peter M., Palendira, Umaimainthan, Menzies, Alexander M., Long, Georgina V., Scolyer, Richard A., Wilmott, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343795/
https://ncbi.nlm.nih.gov/pubmed/30713793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1537581
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