Enhanced NAMPT-Mediated NAD Salvage Pathway Contributes to Psoriasis Pathogenesis by Amplifying Epithelial Auto-Inflammatory Circuits

Dysregulated cross-talk between immune cells and epithelial compartments is responsible for the onset and amplification of pathogenic auto-inflammatory circuits occurring in psoriasis. NAMPT-mediated NAD salvage pathway has been recently described as an immunometabolic route having inflammatory func...

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Pubblicato in:Int J Mol Sci
Autori principali: Mercurio, Laura, Morelli, Martina, Scarponi, Claudia, Scaglione, Giovanni Luca, Pallotta, Sabatino, Avitabile, Daniele, Albanesi, Cristina, Madonna, Stefania
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267663/
https://ncbi.nlm.nih.gov/pubmed/34202251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136860
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