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NecroX-5 Can Suppress Melanoma Metastasis by Reducing the Expression of Rho-Family GTPases

NecroX-5 (NX-5) is a cell-permeable necrosis inhibitor with cytoprotective effects. Although it has been reported to inhibit lung and breast cancer metastasis by modulating migration, its therapeutic effect on melanoma metastasis is still unknown. In this study, we examined the anti-metastatic effec...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Moon, Gue-Tae, Lee, Ji-Hyun, Jeong, Sang-Hyun, Jin, Song-Wan, Park, Young-Min
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267632/
https://ncbi.nlm.nih.gov/pubmed/34201921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10132790
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