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Modulation of Tumor Microenvironment to Enhance Radiotherapy Efficacy in Esophageal Squamous Cell Carcinoma by Inhibiting Carbonic Anhydrase IX

The radiotherapy outcomes of patients with advanced esophageal squamous cell carcinoma (ESCC) remain poor due to hypoxia. Carbonic anhydrase IX (CAIX) is a membrane-associated enzyme that induces hypoxia, extracellular acidity, and upregulation of hypoxia-related factors in tumor microenvironment, t...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Xu, Pengqin, Zhang, Yu, Ge, Fanghong, Zhang, Fuming, He, Xia, Gao, Xingya
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267588/
https://ncbi.nlm.nih.gov/pubmed/34249682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.637252
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