Modulation of Tumor Microenvironment to Enhance Radiotherapy Efficacy in Esophageal Squamous Cell Carcinoma by Inhibiting Carbonic Anhydrase IX

The radiotherapy outcomes of patients with advanced esophageal squamous cell carcinoma (ESCC) remain poor due to hypoxia. Carbonic anhydrase IX (CAIX) is a membrane-associated enzyme that induces hypoxia, extracellular acidity, and upregulation of hypoxia-related factors in tumor microenvironment, t...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Xu, Pengqin, Zhang, Yu, Ge, Fanghong, Zhang, Fuming, He, Xia, Gao, Xingya
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267588/
https://ncbi.nlm.nih.gov/pubmed/34249682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.637252
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