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Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles
GPR17 is a G-protein-coupled receptor (GPCR) implicated in the regulation of glucose metabolism and energy homeostasis. Such evidence is primarily drawn from mouse knockout studies and suggests GPR17 as a potential novel therapeutic target for the treatment of metabolic diseases. However, links betw...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8267566/ https://ncbi.nlm.nih.gov/pubmed/34144038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100881 |
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