High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity

Cytotoxic T lymphocytes (CTLs) are key players to eliminate tumorigenic or pathogen-infected cells using lytic granules (LG) and Fas ligand (FasL) pathways. Depletion of glucose leads to severely impaired cytotoxic function of CTLs. However, the impact of excessive glucose on CTL functions still rem...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhu, Jie, Yang, Wenjuan, Zhou, Xiangda, Zöphel, Dorina, Soriano-Baguet, Leticia, Dolgener, Denise, Carlein, Christopher, Hof, Chantal, Zhao, Renping, Ye, Shandong, Schwarz, Eva C., Brenner, Dirk, Prates Roma, Leticia, Qu, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267470/
https://ncbi.nlm.nih.gov/pubmed/34248978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.689337
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