High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity

Cytotoxic T lymphocytes (CTLs) are key players to eliminate tumorigenic or pathogen-infected cells using lytic granules (LG) and Fas ligand (FasL) pathways. Depletion of glucose leads to severely impaired cytotoxic function of CTLs. However, the impact of excessive glucose on CTL functions still rem...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Zhu, Jie, Yang, Wenjuan, Zhou, Xiangda, Zöphel, Dorina, Soriano-Baguet, Leticia, Dolgener, Denise, Carlein, Christopher, Hof, Chantal, Zhao, Renping, Ye, Shandong, Schwarz, Eva C., Brenner, Dirk, Prates Roma, Leticia, Qu, Bin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8267470/
https://ncbi.nlm.nih.gov/pubmed/34248978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.689337
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