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A myostatin-CCL20–CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis

The interactions of fibroblast-like synoviocyte (FLS)-derived pro-inflammatory cytokines/chemokines and immune cells support the recruitment and activation of inflammatory cells in RA. Here, we show for the first time that the classical myokine myostatin (GDF-8) is involved in the recruitment of Th1...

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發表在:Sci Rep
Main Authors: Fennen, Michelle, Weinhage, Toni, Kracke, Vanessa, Intemann, Johanna, Varga, Georg, Wehmeyer, Corinna, Foell, Dirk, Korb-Pap, Adelheid, Pap, Thomas, Dankbar, Berno
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266846/
https://ncbi.nlm.nih.gov/pubmed/34239010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93599-6
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