Deficiency of fibroblast activation protein alpha ameliorates cartilage destruction in inflammatory destructive arthritis

INTRODUCTION: Inflammatory destructive arthritis, like rheumatoid arthritis (RA), is characterized by invasion of synovial fibroblasts (SF) into the articular cartilage and erosion of the underlying bone, leading to progressive joint destruction. Because fibroblast activation protein alpha (FAP) has...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Wäldele, Stefan, Koers-Wunrau, Christina, Beckmann, Denise, Korb-Pap, Adelheid, Wehmeyer, Corinna, Pap, Thomas, Dankbar, Berno
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335697/
https://ncbi.nlm.nih.gov/pubmed/25600705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0524-6
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