c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability

c-FLIP (cellular FLICE-like inhibitory protein) protein is mostly known as an apoptosis modulator. However, increasing data underline that c-FLIP plays multiple roles in cellular homoeostasis, influencing differently the same pathways depending on its expression level and isoform predominance. Few a...

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Pubblicato in:Cell Death Dis
Autori principali: Tomaipitinca, Luana, Petrungaro, Simonetta, D’Acunzo, Pasquale, Facchiano, Angelo, Dubey, Amit, Rizza, Salvatore, Giulitti, Federico, Gaudio, Eugenio, Filippini, Antonio, Ziparo, Elio, Cecconi, Francesco, Giampietri, Claudia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266807/
https://ncbi.nlm.nih.gov/pubmed/34238932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03957-5
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