Multifaceted Roles of GSK-3 in Cancer and Autophagy-Related Diseases

GSK-3 is a ubiquitously expressed serine/threonine kinase existing as GSK-3α and GSK-3β isoforms, both active under basal conditions and inactivated upon phosphorylation by different upstream kinases. Initially discovered as a regulator of glycogen synthesis, GSK-3 is also involved in several signal...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Mancinelli, Romina, Carpino, Guido, Petrungaro, Simonetta, Mammola, Caterina Loredana, Tomaipitinca, Luana, Filippini, Antonio, Facchiano, Antonio, Ziparo, Elio, Giampietri, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742885/
https://ncbi.nlm.nih.gov/pubmed/29379583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4629495
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