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Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer

Exosomes are carriers of intercellular information that regulate the tumor microenvironment, and they have an essential role in drug resistance through various mechanisms such as transporting RNA molecules and proteins. Nevertheless, their effects on gemcitabine resistance in triple-negative breast...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Li, Ting, Tao, Zhonghua, Zhu, Yihui, Liu, Xiaojia, Wang, Leiping, Du, Yiqun, Cao, Jun, Wang, Biyun, Zhang, Jian, Hu, Xichun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266800/
https://ncbi.nlm.nih.gov/pubmed/34238922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03963-7
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