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Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer

Exosomes are carriers of intercellular information that regulate the tumor microenvironment, and they have an essential role in drug resistance through various mechanisms such as transporting RNA molecules and proteins. Nevertheless, their effects on gemcitabine resistance in triple-negative breast...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Li, Ting, Tao, Zhonghua, Zhu, Yihui, Liu, Xiaojia, Wang, Leiping, Du, Yiqun, Cao, Jun, Wang, Biyun, Zhang, Jian, Hu, Xichun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266800/
https://ncbi.nlm.nih.gov/pubmed/34238922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03963-7
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