Exosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer

Exosomes are carriers of intercellular information that regulate the tumor microenvironment, and they have an essential role in drug resistance through various mechanisms such as transporting RNA molecules and proteins. Nevertheless, their effects on gemcitabine resistance in triple-negative breast...

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Publicado no:Cell Death Dis
Main Authors: Li, Ting, Tao, Zhonghua, Zhu, Yihui, Liu, Xiaojia, Wang, Leiping, Du, Yiqun, Cao, Jun, Wang, Biyun, Zhang, Jian, Hu, Xichun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266800/
https://ncbi.nlm.nih.gov/pubmed/34238922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03963-7
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