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12-Epi-Napelline Inhibits Leukemia Cell Proliferation via the PI3K/AKT Signaling Pathway In Vitro and In Vivo

This study aimed to investigate the inhibitory effect of 12-epi-napelline on leukemia cells and its possible mechanisms. The inhibitory effects of 12-epi-napelline on K-562 and HL-60 cells were evaluated using the CCK-8 assay, cell cycle arrest and apoptosis were detected by flow cytometry, and the...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Han, Jia, Hou, Wei, Cai, Bi-qing, Zhang, Fan, Tang, Jian-cai
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266464/
https://ncbi.nlm.nih.gov/pubmed/34306152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6687519
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