Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling

Neutrophil elastase (NE) is a neutrophil-derived serine proteinase with specificity for a broad range of substrates. NE has been reported to be associated with the pathogenesis of several conditions, particularly that of pulmonary diseases. Previous studies have shown that NE can cleave the pro-myel...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: YANG, RONG, ZHONG, LIANG, YANG, XIAO-QUN, JIANG, KAI-LING, LI, LIU, SONG, HAO, LIU, BEI-ZHONG
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838072/
https://ncbi.nlm.nih.gov/pubmed/27035679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5051
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