Potential Role for the RASD1 Glucocorticoid-Responsive Gene in Corticotroph Tumorigenesis

Introduction: Originally identified due to its dexamethasone inducibility in mouse corticotropinoma AtT20 cells, RASD1 is a receptor-independent activator of G-proteins, via guanine nucleotide exchange factor (GEF) activity. It remains unclear, however, whether, and if so, how RASD1 mediates the eff...

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Udgivet i:J Endocr Soc
Main Authors: Hernández-Ramírez, Laura C, Pankratz, Nathan, Lane, John, Hu, Mingming, Faucz, Fabio R, Chittiboina, Prashant, Denise, Kay M, Mills, James L, Stratakis, Constantine A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Neuroendocrinology and Pituitary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265992/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1118
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