Large Genomic Aberrations in Corticotropinomas Are Associated With Greater Aggressiveness

CONTEXT: Genomic losses/gains are associated with cancer progression and prognosis. In pituitary adenomas, analyses of copy number variations (CNVs) have shown that a subset of adenomas have higher genomic variability. However, whether CNVs are associated with tumor aggressiveness and prognosis has...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Tatsi, Christina, Pankratz, Nathan, Lane, John, Faucz, Fabio R, Hernández-Ramírez, Laura C, Keil, Margaret, Trivellin, Giampaolo, Chittiboina, Prashant, Mills, James L, Stratakis, Constantine A, Lodish, Maya B
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452317/
https://ncbi.nlm.nih.gov/pubmed/30597087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-02164
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