Large Genomic Aberrations in Corticotropinomas Are Associated With Greater Aggressiveness

CONTEXT: Genomic losses/gains are associated with cancer progression and prognosis. In pituitary adenomas, analyses of copy number variations (CNVs) have shown that a subset of adenomas have higher genomic variability. However, whether CNVs are associated with tumor aggressiveness and prognosis has...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Endocrinol Metab
Auteurs principaux: Tatsi, Christina, Pankratz, Nathan, Lane, John, Faucz, Fabio R, Hernández-Ramírez, Laura C, Keil, Margaret, Trivellin, Giampaolo, Chittiboina, Prashant, Mills, James L, Stratakis, Constantine A, Lodish, Maya B
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2018
Sujets:
Clinical Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452317/
https://ncbi.nlm.nih.gov/pubmed/30597087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-02164
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