Characterization of Viral Insulin-Like Peptides Reveals Unique White Adipose Tissue Specific Characteristics

The members of the insulin superfamily are well conserved across the evolution tree. We recently showed that four viruses in the Iridoviridae family possess genes that share high similarity with human insulin and IGF-1. By chemically synthesizing single chain (sc, IGF-1 like) forms of these viral in...

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Bibliografiske detaljer
Udgivet i:J Endocr Soc
Main Authors: Chrudinova, Martina, Francois, Moreau, Noh, Hye Lim, Panikova, Terezie, Zakova, Lenka, Friedline, Randall H, Alsina-Fernandez, Jorge, Kim, Jason K, Jiracek, Jiri, Kahn, Ronald C, Altindis, Emrah
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Diabetes Mellitus and Glucose Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265932/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.892
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