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Effects of Natalizumab Therapy on Intrathecal Immunoglobulin G Production Indicate Targeting of Plasmablasts
OBJECTIVES: To evaluate the long-term effects of natalizumab (NTZ) on different features of intrathecal immunoglobulin (Ig) synthesis in patients with multiple sclerosis (MS) and to quantify the expression of α4-integrin in stages of B-cell maturation. METHODS: We combined a cross-sectional (49 NTZ-...
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| 出版年: | Neurol Neuroimmunol Neuroinflamm |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Lippincott Williams & Wilkins
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8265584/ https://ncbi.nlm.nih.gov/pubmed/34210800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000001030 |
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