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Effect of Body Weight on Age at Onset in Huntington Disease: A Mendelian Randomization Study

OBJECTIVE: Weight loss is associated with clinical progression in Huntington disease (HD), but whether body weight causally affects disease onset or progression is unknown. Therefore, we aimed to assess whether genetically determined variations in body weight are causally related to age at onset in...

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Detalhes bibliográficos
Publicado no:Neurol Genet
Main Authors: van der Burg, Jorien M.M., Weydt, Patrick, Landwehrmeyer, Georg Bernhard, Aziz, N. Ahmad
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265577/
https://ncbi.nlm.nih.gov/pubmed/34250226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000603
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