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Overlap between age-at-onset and disease-progression determinants in Huntington disease

OBJECTIVE: A fundamental but still unresolved issue regarding Huntington disease (HD) pathogenesis is whether the factors that determine age at onset are the same as those that govern disease progression. Because elucidation of this issue is crucial for the development as well as optimal timing of a...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Aziz, N. Ahmad, van der Burg, Jorien M.M., Tabrizi, Sarah J., Landwehrmeyer, G. Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996832/
https://ncbi.nlm.nih.gov/pubmed/29743208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005690
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