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Overlap between age-at-onset and disease-progression determinants in Huntington disease

OBJECTIVE: A fundamental but still unresolved issue regarding Huntington disease (HD) pathogenesis is whether the factors that determine age at onset are the same as those that govern disease progression. Because elucidation of this issue is crucial for the development as well as optimal timing of a...

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Vydáno v:Neurology
Hlavní autoři: Aziz, N. Ahmad, van der Burg, Jorien M.M., Tabrizi, Sarah J., Landwehrmeyer, G. Bernhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996832/
https://ncbi.nlm.nih.gov/pubmed/29743208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005690
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