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Measuring RAN peptide toxicity in C. elegans
C. elegans is commonly used to model age-related neurodegenerative diseases caused by repeat expansion mutations, such as Amyotrophic Lateral Sclerosis (ALS) and Huntington’s disease. Recently, repeat expansion-containing RNA was shown to be the substrate for a novel type of protein translation call...
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| Veröffentlicht in: | J Vis Exp |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8265314/ https://ncbi.nlm.nih.gov/pubmed/32420986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/61024 |
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