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PolyQ-independent toxicity associated with novel translational products from CAG repeat expansions
Expanded CAG nucleotide repeats are the underlying genetic cause of at least 14 incurable diseases, including Huntington’s disease (HD). The toxicity associated with many CAG repeat expansions is thought to be due to the translation of the CAG repeat to create a polyQ protein, which forms toxic olig...
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| 出版年: | PLoS One |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7117740/ https://ncbi.nlm.nih.gov/pubmed/32240172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227464 |
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