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PolyQ-independent toxicity associated with novel translational products from CAG repeat expansions
Expanded CAG nucleotide repeats are the underlying genetic cause of at least 14 incurable diseases, including Huntington’s disease (HD). The toxicity associated with many CAG repeat expansions is thought to be due to the translation of the CAG repeat to create a polyQ protein, which forms toxic olig...
Guardat en:
| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7117740/ https://ncbi.nlm.nih.gov/pubmed/32240172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227464 |
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