Prevalence of Five Pharmacologically Most Important CYP2C9 and CYP2C19 Allelic Variants in the Population from the Republic of Srpska in Bosnia and Herzegovina

The enzymes of the cytochrome P450 superfamily play a critical role in phase I drug metabolism. Among them, CYP2C9 and CYP2C19 are clinically important, as they can mediate severe toxicity, therapy failure, and increased susceptibility to cancer and other diseases caused by chemicals. The aim of thi...

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Bibliografiske detaljer
Udgivet i:Arh Hig Rada Toksikol
Main Authors: Vidović, Stojko, Škrbić, Ranko, Stojiljković, Miloš P., Vidović, Vanja, Bećarević, Jelena, Stoisavljević-Šatara, Svjetlana, Maksimović, Nela
Format: Artigo
Sprog:Inglês
Udgivet: Sciendo 2021
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265196/
https://ncbi.nlm.nih.gov/pubmed/34187105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/aiht-2021-72-3499
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