Prevalence of Five Pharmacologically Most Important CYP2C9 and CYP2C19 Allelic Variants in the Population from the Republic of Srpska in Bosnia and Herzegovina

The enzymes of the cytochrome P450 superfamily play a critical role in phase I drug metabolism. Among them, CYP2C9 and CYP2C19 are clinically important, as they can mediate severe toxicity, therapy failure, and increased susceptibility to cancer and other diseases caused by chemicals. The aim of thi...

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Detalhes bibliográficos
Publicado no:Arh Hig Rada Toksikol
Main Authors: Vidović, Stojko, Škrbić, Ranko, Stojiljković, Miloš P., Vidović, Vanja, Bećarević, Jelena, Stoisavljević-Šatara, Svjetlana, Maksimović, Nela
Formato: Artigo
Idioma:Inglês
Publicado em: Sciendo 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265196/
https://ncbi.nlm.nih.gov/pubmed/34187105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/aiht-2021-72-3499
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