5-aza-2′-deoxycitidine inhibits cell proliferation, extracellular matrix formation and Wnt/β-catenin pathway in human uterine leiomyomas

BACKGROUND: Uterine leiomyoma is a benign tumor with unclear pathogenesis and inaccurate treatment. This tumor exhibits altered DNA methylation related to disease progression. DNMT inhibitors as 5-aza-2′-deoxycytidine (5-aza-CdR), have been suggested to treat tumors in which DNA methylation is alter...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Principais autores: Carbajo-García, María Cristina, Corachán, Ana, Segura-Benitez, Marina, Monleón, Javier, Escrig, Julia, Faus, Amparo, Pellicer, Antonio, Cervelló, Irene, Ferrero, Hortensia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265104/
https://ncbi.nlm.nih.gov/pubmed/34233687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-021-00790-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados