Nalaganje...

A bivalent protein targeting glycans and HR1 domain in spike protein potently inhibited infection of SARS-CoV-2 and other human coronaviruses

BACKGROUND: Our previous studies have shown that combining the antiviral lectin GRFT and the pan-CoV fusion inhibitory peptide EK1 results in highly potent inhibitory activity against SARS-CoV-2 infection. In this study, we aimed to design and construct a bivalent protein consisting of GRFT and EK1...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Biosci
Main Authors: Cai, Yanxing, Xu, Wei, Tang, Jiayi, Cao, Najing, Lan, Qiaoshuai, Lu, Lu, Jiang, Shibo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264481/
https://ncbi.nlm.nih.gov/pubmed/34238357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00638-w
Oznake: Označite
Brez oznak, prvi označite!