Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function

OBJECTIVES: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. Janus Kinase inhibitors (JAKi) have emerged as an encouraging class of drugs for the treatment of PsA. Here, we compare the effect of four JAKi on primary PsA synovial fibroblasts (PsAFLS) activation,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Immunol
मुख्य लेखकों: O’Brien, Aisling, Hanlon, Megan Mary, Marzaioli, Viviana, Wade, Siobhan C., Flynn, Keelin, Fearon, Ursula, Veale, Douglas J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2021
विषय:
Immunology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264423/
https://ncbi.nlm.nih.gov/pubmed/34248953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.672461
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