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Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence

Lipotoxicity, caused by intracellular lipid accumulation, accelerates the degenerative process of cellular senescence, which has implications in cancer development and therapy. Previously, carnitine palmitoyltransferase 1C (CPT1C), a mitochondrial enzyme that catalyzes carnitinylation of fatty acids...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Zhang, Huizhen, Wang, Yongtao, Guan, Lihuan, Chen, Yixin, Chen, Panpan, Sun, Jiahong, Gonzalez, Frank J., Huang, Min, Bi, Huichang
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264383/
https://ncbi.nlm.nih.gov/pubmed/34277122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2020.04.004
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