Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence

Lipotoxicity, caused by intracellular lipid accumulation, accelerates the degenerative process of cellular senescence, which has implications in cancer development and therapy. Previously, carnitine palmitoyltransferase 1C (CPT1C), a mitochondrial enzyme that catalyzes carnitinylation of fatty acids...

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Bibliografiset tiedot
Julkaisussa:J Pharm Anal
Päätekijät: Zhang, Huizhen, Wang, Yongtao, Guan, Lihuan, Chen, Yixin, Chen, Panpan, Sun, Jiahong, Gonzalez, Frank J., Huang, Min, Bi, Huichang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Xi'an Jiaotong University 2021
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Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264383/
https://ncbi.nlm.nih.gov/pubmed/34277122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2020.04.004
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