Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence

Lipotoxicity, caused by intracellular lipid accumulation, accelerates the degenerative process of cellular senescence, which has implications in cancer development and therapy. Previously, carnitine palmitoyltransferase 1C (CPT1C), a mitochondrial enzyme that catalyzes carnitinylation of fatty acids...

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Bibliografski detalji
Izdano u:J Pharm Anal
Glavni autori: Zhang, Huizhen, Wang, Yongtao, Guan, Lihuan, Chen, Yixin, Chen, Panpan, Sun, Jiahong, Gonzalez, Frank J., Huang, Min, Bi, Huichang
Format: Artigo
Jezik:Inglês
Izdano: Xi'an Jiaotong University 2021
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264383/
https://ncbi.nlm.nih.gov/pubmed/34277122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2020.04.004
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