Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence

Lipotoxicity, caused by intracellular lipid accumulation, accelerates the degenerative process of cellular senescence, which has implications in cancer development and therapy. Previously, carnitine palmitoyltransferase 1C (CPT1C), a mitochondrial enzyme that catalyzes carnitinylation of fatty acids...

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Bibliografiske detaljer
Udgivet i:J Pharm Anal
Main Authors: Zhang, Huizhen, Wang, Yongtao, Guan, Lihuan, Chen, Yixin, Chen, Panpan, Sun, Jiahong, Gonzalez, Frank J., Huang, Min, Bi, Huichang
Format: Artigo
Sprog:Inglês
Udgivet: Xi'an Jiaotong University 2021
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264383/
https://ncbi.nlm.nih.gov/pubmed/34277122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2020.04.004
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