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Circulating Mitochondrial DNA Stimulates Innate Immune Signaling Pathways to Mediate Acute Kidney Injury

Mitochondrial dysfunction is increasingly considered as a critical contributor to the occurrence and progression of acute kidney injury (AKI). However, the mechanisms by which damaged mitochondria mediate AKI progression are multifactorial and complicated. Mitochondrial DNA (mtDNA) released from dam...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Liu, Jiaye, Jia, Zhanjun, Gong, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264283/
https://ncbi.nlm.nih.gov/pubmed/34248963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.680648
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