Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN

The innate immune and host-protective responses to viruses, such as the airway pathogen human metapneumovirus (HMPV), depend on interferons (IFNs) that is induced through TANK-binding kinase 1 (TBK1) and IFN regulatory factors (IRFs). The transcription factor IRF1 is important for host resistance ag...

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Pubblicato in:Front Immunol
Autori principali: Loevenich, Simon, Spahn, Alix S., Rian, Kristin, Boyartchuk, Victor, Anthonsen, Marit Walbye
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264192/
https://ncbi.nlm.nih.gov/pubmed/34248923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.563336
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