Concentration-dependent alpha(1)-Adrenoceptor Antagonism and Inhibition of Neurogenic Smooth Muscle Contraction by Mirabegron in the Human Prostate

Introduction: Mirabegron is available for treatment of storage symptoms in overactive bladder, which may be improved by β(3)-adrenoceptor-induced bladder smooth muscle relaxation. In addition to storage symptoms, lower urinary tract symptoms in men include obstructive symptoms attributed to benign p...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Huang, Ru, Liu, Yuhan, Ciotkowska, Anna, Tamalunas, Alexander, Waidelich, Raphaela, Strittmatter, Frank, Stief, Christian G., Hennenberg, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264149/
https://ncbi.nlm.nih.gov/pubmed/34248624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.666047
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