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P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate

Prostate smooth muscle tone and hyperplastic growth are involved in the pathophysiology and treatment of male lower urinary tract symptoms (LUTS). Available drugs are characterized by limited efficacy. Patients’ adherence is particularly low to combination therapies of 5α-reductase inhibitors and α(...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Wang, Yiming, Gratzke, Christian, Tamalunas, Alexander, Wiemer, Nicolas, Ciotkowska, Anna, Rutz, Beata, Waidelich, Raphaela, Strittmatter, Frank, Liu, Chunxiao, Stief, Christian G., Hennenberg, Martin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829229/
https://ncbi.nlm.nih.gov/pubmed/27071060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153312
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