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P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate

Prostate smooth muscle tone and hyperplastic growth are involved in the pathophysiology and treatment of male lower urinary tract symptoms (LUTS). Available drugs are characterized by limited efficacy. Patients’ adherence is particularly low to combination therapies of 5α-reductase inhibitors and α(...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Wang, Yiming, Gratzke, Christian, Tamalunas, Alexander, Wiemer, Nicolas, Ciotkowska, Anna, Rutz, Beata, Waidelich, Raphaela, Strittmatter, Frank, Liu, Chunxiao, Stief, Christian G., Hennenberg, Martin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829229/
https://ncbi.nlm.nih.gov/pubmed/27071060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153312
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