Irradiation-Modulated Murine Brain Microenvironment Enhances GL261-Tumor Growth and Inhibits Anti-PD-L1 Immunotherapy

PURPOSE: Clinical evidence suggests radiation induces changes in the brain microenvironment that affect subsequent response to treatment. This study investigates the effect of previous radiation, delivered six weeks prior to orthotopic tumor implantation, on subsequent tumor growth and therapeutic r...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Garbow, Joel R., Johanns, Tanner M., Ge, Xia, Engelbach, John A., Yuan, Liya, Dahiya, Sonika, Tsien, Christina I., Gao, Feng, Rich, Keith M., Ackerman, Joseph J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263916/
https://ncbi.nlm.nih.gov/pubmed/34249742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.693146
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