The molecular basis for SARS-CoV-2 binding to dog ACE2

SARS-CoV-2 can infect many domestic animals, including dogs. Herein, we show that dog angiotensin-converting enzyme 2 (dACE2) can bind to the SARS-CoV-2 spike (S) protein receptor binding domain (RBD), and that both pseudotyped and authentic SARS-CoV-2 can infect dACE2-expressing cells. We solved th...

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I publikationen:Nat Commun
Huvudupphovsmän: Zhang, Zengyuan, Zhang, Yanfang, Liu, Kefang, Li, Yan, Lu, Qiong, Wang, Qingling, Zhang, Yuqin, Wang, Liang, Liao, Hanyi, Zheng, Anqi, Ma, Sufang, Fan, Zheng, Li, Huifang, Huang, Weijin, Bi, Yuhai, Zhao, Xin, Wang, Qihui, Gao, George F., Xiao, Haixia, Tong, Zhou, Qi, Jianxun, Sun, Yeping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263772/
https://ncbi.nlm.nih.gov/pubmed/34234119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24326-y
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