A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

Neutralizing antibodies could potentially be used as antivirals against the coronavirus disease 2019 (COVID-19) pandemic. Here, we report isolation of four human-origin monoclonal antibodies from a convalescent patient, all of which display neutralization abilities. The antibodies B38 and H4 block b...

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Publicado en:Science
Main Authors: Wu, Yan, Wang, Feiran, Shen, Chenguang, Peng, Weiyu, Li, Delin, Zhao, Cheng, Li, Zhaohui, Li, Shihua, Bi, Yuhai, Yang, Yang, Gong, Yuhuan, Xiao, Haixia, Fan, Zheng, Tan, Shuguang, Wu, Guizhen, Tan, Wenjie, Lu, Xuancheng, Fan, Changfa, Wang, Qihui, Liu, Yingxia, Zhang, Chen, Qi, Jianxun, Gao, George Fu, Gao, Feng, Liu, Lei
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7223722/
https://ncbi.nlm.nih.gov/pubmed/32404477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc2241
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