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NONO phase separation enhances DNA damage repair by accelerating nuclear EGFR-induced DNA-PK activation

Radioresistance is one of the main causes of cancer treatment failure, which leads to relapse and inferior survival outcome of cancer patients. Liquid-liquid phase separation (LLPS) of proteins is known to be involved in various biological processes, whereas its role in the regulation of radiosensit...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Fan, Xin-Juan, Wang, Yun-Long, Zhao, Wan-Wen, Bai, Shao-Mei, Ma, Yan, Yin, Xin-Ke, Feng, Li-Li, Feng, Wei-Xing, Wang, Ying-Nai, Liu, Quentin, Hung, Mien-Chie, Wan, Xiang-Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263645/
https://ncbi.nlm.nih.gov/pubmed/34249431
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