RANKL expression in chondrocytes and its promotion by lymphotoxin-α in the course of cartilage destruction during rheumatoid arthritis

We investigated the expression and localization of the receptor activator nuclear factor κB ligand (RANKL) in cartilage from patients with rheumatoid arthritis (RA) of relevance to cartilage degeneration. We also examined the role of exogenous lymphotoxin (LT)-α on RANKL expression in human chondroc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Takeshita, Ayumu, Nishida, Keiichiro, Yoshida, Aki, Nasu, Yoshihisa, Nakahara, Ryuichi, Kaneda, Daisuke, Ohashi, Hideki, Ozaki, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263262/
https://ncbi.nlm.nih.gov/pubmed/34234380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254268
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