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RANKL expression in chondrocytes and its promotion by lymphotoxin-α in the course of cartilage destruction during rheumatoid arthritis

We investigated the expression and localization of the receptor activator nuclear factor κB ligand (RANKL) in cartilage from patients with rheumatoid arthritis (RA) of relevance to cartilage degeneration. We also examined the role of exogenous lymphotoxin (LT)-α on RANKL expression in human chondroc...

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Vydáno v:PLoS One
Hlavní autoři: Takeshita, Ayumu, Nishida, Keiichiro, Yoshida, Aki, Nasu, Yoshihisa, Nakahara, Ryuichi, Kaneda, Daisuke, Ohashi, Hideki, Ozaki, Toshifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263262/
https://ncbi.nlm.nih.gov/pubmed/34234380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254268
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