EPCT-03. SERIAL PLASMA AND CSF CELL-FREE TUMOR DNA (CF-TDNA) TRACKING IN DIFFUSE MIDLINE GLIOMA PATIENTS UNDERGOING TREATMENT WITH ONC201

Diffuse midline glioma (DMG) with the H3K27M mutation is a lethal childhood brain cancer, with patients rarely surviving 2 years from diagnosis. We conducted a multi-site Phase 1 trial of the imipridone ONC201 for children with H3K27M-mutant glioma (NCT03416530). Patients enrolled on Arm D of the tr...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Cantor, Evan, Wierzbicki, Kyle, Tarapore, Rohinton S, Thomas, Chase, Cartaxo, Rodrigo, Yadav, Viveka Nand, Ravindran, Ramya, Bruzek, Amy K, Wadden, Jack, Babilla, Clarissa May, Kawakibi, Abed Rhaman, Ji, Sunjong, Ramos, Johanna, Paul, Alyssa, Wolfe, Ian, Leonard, Marcia, Robertson, Partricia, Franson, Andrea, Mody, Rajen, Garton, Hugh, Odia, Yazmin, Kline, Cassie, Vitanza, Nicholas A, Khatua, Soumen, Mueller, Sabine, Allen, Joshua E, Gardner, Sharon, Koschmann, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Translational/Early Phase Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263166/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.189
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