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Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells

Pericentromeric heterochromatin (PCH), the constitutive heterochromatin of pericentromeric regions, plays crucial roles in various cellular events, such as cell division and DNA replication. PCH forms chromocenters in the interphase nucleus, and chromocenters cluster at the prophase of meiosis. Chro...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Hagihara, Yota, Asada, Satoshi, Maeda, Takahiro, Nakano, Toru, Yamaguchi, Shinpei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263065/
https://ncbi.nlm.nih.gov/pubmed/34166371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009646
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