Evaluation of vanillin as a probe drug for aldehyde oxidase and phenotyping for its activity in a Western Indian Cohort

BACKGROUND: Aldehyde oxidase (AO), a molybdoflavoenzyme, is emerging as a key player in drug discovery and metabolism. Despite having several known substrates, there are no validated probes reported for studying the activity of AO in vivo. Vanillin (4-hydroxy 3-methoxy benzaldehyde) is an excellent...

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Publicat a:Indian J Pharmacol
Autors principals: Subash, Sandhya, Gogtay, Nithya J, Iyer, Krishna R, Gandhe, Prajakta, Budania, Ritu, Thatte, Urmila M
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer - Medknow 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262417/
https://ncbi.nlm.nih.gov/pubmed/34169906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/ijp.IJP_463_18
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